NMDP Donor For All Initiative
Unlocking access to life-saving treatment
In the past, having an 8/8 human leukocyte antigen (HLA)-matched donor was crucial for the best hematopoietic cell transplant (HCT) outcomes. The problem: even though every search through NMDP℠ provides patients access to more than 41 million potential volunteer donors worldwide, not every patient in need has a full match—especially those with ethnically diverse ancestries. And even if every eligible donor in the United States joined the NMDP Registry℠ and was willing to donate, a substantial gap would remain leaving patients without an 8/8 donor.
At NMDP, we refuse to accept the status quo. We’re on a mission to unlock access to treatment through innovative research that significantly expands options for suitable donors for those without a fully matched donor.
Because registry member recruitment efforts alone won’t solve the need. Science will.
Transplant recipient, Johanna, with her donor, Catherine
Increasing the odds for all patients
Our Donor for All initiative includes many research efforts that aim to establish a new safe and effective approach for using mismatched unrelated donor (MMUD) transplants in the U.S. and abroad.
This will significantly increase the odds that patients with diverse ancestry will find a suitably matched available donor on the NMDP Registry—all while providing equal outcomes comparable to current survival rates with an 8/8 matched donor. Explore the work that's increasing the odds your patient will find a life-saving match.
Then connect with a NMDP clinical operations partner in your region to discuss the Donor for All initiative and how you can get involved.
Breakthrough research brings life-saving treatments to more patients
Watch this video for additional background on why MMUD transplant research is critical and take a closer look at the 15-MMUD clinical trial results.
Donor for All initiative clinical trials
15-MMUD clinical trial
ACCESS clinical trial
OPTIMIZE clinical trial
Donor for All initiative observational studies
PTCy equalizes MUD and MMUD HCT outcomes
MMUDs expand access for nearly 100% of patients
Articles and news
Breaking HLA-related barriers in alloHCT
PTCy offers new hope for MMUD HCT
Contact our team
Questions about the Donor for All initiative, MMUD clinical trials or how you can get involved? Talk to your NMDP clinical operations partner or fill out the form and a clinical operations partner in your region will connect with you.