Quality of Life Pre and Post Transplant
The Role of Transplant for Treating MDS in Older Patients
March 17, 2022
Target Audience
This educational activity is intended for physicians, nurses and other members of the health care team who care for patients who may benefit from hematopoietic stem cell transplantation.
Program Overview
The results of recent research on hematopoietic cell transplantation (HCT) for older adults with high-risk MDS has implications for community hematologists/oncologists. During this 60-minute on-demand webinar, the panel explores the implications from the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 1102 study— a multicenter, biologic assignment trial in older patients with high-risk MDS to define the benefit of HCT over non-HCT therapy.
Those results include a finding that demonstrates quality of life and functional performance status are better than age when determining eligibility for HCT for older patients with high-risk MDS. With HCT remaining the only curative therapy for MDS, those factors must be taken into consideration when assessing treatment options for older patients with high-risk MDS.
Interested in claiming CME or CE credit?
Be sure to complete the pre-test, then complete the post-test after watching the webinar. The post-test link can be found in the on-demand webinar platform in the related resources tab. For more information, see the instructions for participation and requesting credit below.
Learning Objectives
Upon completion of this course, the learners should be able to:
- Review the BMT CTN 1102 study results
- Explain how quality of life and functional performance status are better than age in determining eligibility for HCT
- Describe how advances in HCT facilitate improved survival and preserve quality of life
- Discuss the implications of the study findings for community hematologists/oncologists who see patients with MDS
- Describe the best practices for referring patients to a transplant center early for HCT consultation
Faculty
Abhinav B. Chandra, MD, MSc, FACP, MBA
Medical Director
Yuma Regional Medical Center Cancer Center
Corey S. Cutler, MD, MPH, FRCP(C)
Medical Director (Stem Cell Transplantation Program)
Dana-Farber Cancer Institute
Associate Professor of Medicine
Harvard Medical School
Rachel Cusatis, PhD
Assistant Professor of Medicine
Medical College of Wisconsin
Scientific Director of Patient Centered Research & Survivorship
CIBMTR® (Center for International Blood and Marrow Transplant Research®)
Stephen Spellman, MBS
Vice President of Research and Senior Scientific Director
CIBMTR
NMDP
Tamila Kindwall-Keller, DO
Professor of Medicine
Medical Director (Cellular Immunotherapy and Stem Cell Transplant Program)
MetroHealth Medical Center
Planning Committee
Abhinav B. Chandra, MD, MSc, FACP, MBA
Medical Director
Yuma Regional Medical Center Cancer Center
Anna Cincotta, FNP
Senior Clinical Operations Partner
NMDP
Corey S. Cutler, MD, MPH, FRCP(C)
Medical Director (Stem Cell Transplantation Program)
Dana-Farber Cancer Institute
Associate Professor of Medicine
Harvard Medical School
Heather Stefanski, MD, PhD
Vice President of Medical Services
NMDP
Rachel Cusatis, PhD
Assistant Professor of Medicine
Medical College of Wisconsin
Scientific Director of Patient Centered Research & Survivorship
CIBMTR® (Center for International Blood and Marrow Transplant Research®)
Stephen Spellman, MBS
Vice President of Research and Senior Scientific Director
CIBMTR
NMDP
Tamila Kindwall-Keller, DO
Professor of Medicine
Medical Director (Cellular Immunotherapy and Stem Cell Transplant Program)
MetroHealth Medical Center
Instructions for participation and request credit
There are no fees for participating and receiving credit for this activity. Successful completion is achieved by reviewing the CE information, completing the pre-test, completing the activity, and completing the post-test and evaluation form. A score of at least 75% on the post-test is required to successfully complete this activity. The participant may take the test until successfully passed.
If you are requesting AMA credits, ANCC credits or a certificate of participation, your certificate will be available for download.
Accredited provider
This activity is jointly provided by The France Foundation and NMDP.Accreditation statement
In support of improving patient care, this activity has been planned and implemented by The France Foundation and NMDP. The France Foundation is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the health care team.
Credit designation
- Physicians: The France Foundation designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
- Nurses: The France Foundation designates this activity for 1.0 contact hour.
- Other healthcare professionals: All other health care professionals completing this course will be issued a statement of participation.
Disclosure policy
In accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education, The France Foundation (TFF) and NMDP require that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial entity. TFF and NMDP resolve all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all their educational programs. Furthermore, TFF and NMDP to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. TFF and NMDP are committed to providing learners with high-quality CME/CE activities that promote improvements in health care and not those of a commercial interest.
Planning committee members, faculty, reviewers, and activity staff have disclosed the following relevant financial relationships. All relevant financial relationships listed have been mitigated.
| Name of Individual | Individual’s Role in Activity | Name of Commercial Entity | Nature of Relationship(s) | Mechanism(s) implemented to resolve conflict of interest |
|---|---|---|---|---|
| Abhinav B. Chandra, MD, MSc, FACP, MBA | Planning Committee Member, Faculty | Tempus Lab | Consultant | All final planning decisions concerning content, learning objectives, and evaluation questions were made by the non-conflicted Planning Committee member Content was reviewed by a non-conflicted member of the Planning Committee to ensure that it is not commercially biased, was fair-balanced, and is based on scientific evidence and/or clinical reasoning. |
| Anna Cincotta, FNP | Planning Committee, Content Reviewer | No relevant financial disclosures | NA | NA |
| Corey S. Cutler, MD, MPH, FRCP(C) | Planning Committee Member, Faculty | No relevant financial disclosures | NA | NA |
| Heather Stefanksi, MD, PhD | Planning Committee, Content Reviewer | Novartis | Non-CE Consulting | The financial relationship with Novartis ended in April 2021. |
| Heather Tarbox, MPH | TFF Staff | No relevant financial disclosures | NA | NA |
| Jas Chahal, PhD | TFF Staff | No relevant financial disclosures | NA | NA |
| Karla Dawson, MPH | NMDP Staff | No relevant financial disclosures | NA | NA |
| Kelly Wilson, MSN, RN | NMDP Staff | No relevant financial disclosures | NA | NA |
| Rachel Cusatis, PhD | Planning Committee, Faculty | No relevant financial disclosures | NA | NA |
| Samantha Watters, MPH | NMDP Staff | No relevant financial disclosures | NA | NA |
| Stephen Spellman, MBS | Planning Committee Member, Moderator | No relevant financial disclosures | NA | NA |
| Tamila Kindwall-Keller, DO | Planning Committee, Faculty | 1. OrcaBIO 2. BMT CTN |
1. Data & Safety Monitoring Board 2. Medical Monitor/ Non-CE Consulting |
All final planning decisions concerning content, learning objectives, and evaluation questions were made by the non-conflicted Planning Committee member.
Content was reviewed by a non-conflicted member of the Planning Committee to ensure that it is not commercially biased, was fair-balanced, and is based on scientific evidence and/or clinical reasoning. |
Disclosure of unlabeled use
TFF and NMDP require CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental, and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of U.S. Food and Drug Administration approved labeling. This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. TFF and NMDP do not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.
Disclaimer
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Contact information
If you have questions about this CME activity, please contact The France Foundation at (860) 434-1650 or info@francefoundation.com.