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HLA & Search Strategy Interactive Learning Series


This self-paced learning experience will help you understand human leukocyte antigen (HLA) and how it applies to the process of hematopoietic cell transplantation (HCT). Early HLA typing helps initiate the donor search promptly to optimize treatment options for patients in need of HCT. The course modules are mobile-friendly but optimized for viewing on a computer, particularly Google Chrome for the best experience.

HLA & Search Strategy Interactive Learning Series

Target Audience

NMDP network partners, community hematology and oncology physicians, transplant physicians, and healthcare professionals in the multidisciplinary team.

Learning Objectives

101: Biology of HLA

  • Describe why HLA matching is important in HCT
  • Define antigen and allele

102: HLA Naming & Typing

  • Describe the components of an HLA allele name
  • Describe the different levels of HLA typing resolution

103: HLA Search Results

  • Define key features of NMDP search results: match category, match grade and match predictions
  • Define how HapLogicSM sorts donors and cord blood units

201: Donor Selection

  • Describe NMDP and the CIBMTR® (Center for International Blood and Marrow Transplant Research®) guidelines regarding optimal unrelated donor selection
  • Basic comprehension of how the NMDP and CIBMTR guidelines apply to donor selection


If you have questions regarding this learning series, email Search Strategy at search-strategies@nmdp.org.